1.Use Views to Insulate Programs from Change
Programming performance-oriented SQL into your programs from the beginning would go a long way toward improving performance overall... and reducing the length of the application development lifecycle.
If you don't work with up-to-date RUNSTATS then you are hobbling the DB2 Optimizer and almost assuredly getting sub-optimal access paths for your DB2 SQL.
This is the answer that can be used for every DB2 question. But if that answer is not followed up with what "it" depends upon, then it is a useless answer... and whoever gave you that answer is probably just trying to get rid of you instead of helping you with your problems.